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Clare Beasley

Primary Area of Research:
Brain, Behaviour & Development

Investigator, BC Children's Hospital
Associate Professor, Department of Psychiatry, Faculty of Medicine, University of British Columbia

Phone: 604 875-2000 ext. 4723
Mailing Address:
BC Children's Hospital
4480 Oak Street
Room A3-115
Vancouver, BC V6H 3N1

 Research Areas

  • Neuropathology of schizophrenia, bipolar disorder and major depressive disorder
  • White matter
  • Inflammation
  • Antipsychotic Drugs
  • Neurodevelopment
  • Proteomics
  • Histology

About Dr. Beasley

The major aim of my research is to identify changes in the brains of individuals with schizophrenia, bipolar disorder and major depressive disorder that may elucidate the etiology of these disorders and provide clues to novel treatments. Current projects focus on white matter pathology and inflammation. In addition, we study the effects of antipsychotic medications on the brain.

Recent publications

Find most recent publications using my ORCID

Selected Publications

Andreazza AC, Barakauskas VE, Fazeli S, Feresten A, Shao L, Wei V, Wu CH, Barr AM, Beasley CL. Effects of haloperidol and clozapine administration on oxidative stress in rat brain, liver and serum. Neurosci Lett. 2015 591:36-40. PMID: 25684243

Hercher C, Chopra V, Beasley CL. Evidence for morphological alterations in prefrontal white matter glia in schizophrenia and bipolar disorder. J Psychiatry Neurosci. 2014 39(6):376-385. PMID: 24936776

Feresten AH, Barakauskas V, Ypsilanti A, Barr AM, Beasley CL. Increased expression of glial fibrillary acidic protein in prefrontal cortex in psychotic illness. Schizophr Res. 2013 150(1):252-257. PMID: 23911257

Epp JR, Beasley CL, Galea LA. Increased hippocampal neurogenesis and p21 expression in depression: dependent on antidepressants, sex, age, and antipsychotic exposure. Neuropsychopharmacology. 2013 38(11):2297-2306. PMID: 23778854

Barr AM, Wu CH, Wong C, Hercher C, Töpfer E, Boyda HN, Procyshyn RM, Honer WG, Beasley CL. Effects of chronic exercise and treatment with the antipsychotic drug olanzapine on hippocampal volume in adult female rats. Neuroscience. 2013 255:147-157. PMID: 24141179

Vila-Rodriguez, F., Honer, W. G., Innis, S. M., Wellington, C. L., & Beasley, C. L. (2011). ApoE and cholesterol in schizophrenia and bipolar disorder: Comparison of grey and white matter and relation with APOE genotype. Journal of Psychiatry & Neuroscience : JPN, 36(1), 47-55. PMID: 20964956 

Barakauskas, V. E., Ypsilanti, A. R., Barr, A. M., Innis, S. M., Honer, W. G., & Beasley, C. L. (2010). Effects of sub-chronic clozapine and haloperidol administration on brain lipid levels. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 34(4), 669-673. PMID: 20227455

Barakauskas, V. E., Beasley, C. L., Barr, A. M., Ypsilanti, A. R., Li, H. Y., Thornton, A. E., Wong, H., Rosokija, G., Mann, J.J., Mancevski, B., Jakovski, Z., Davceva, N., Illevski, B., Dwork, A.J., Falkai, P., & Honer, W. G. (2010). A novel mechanism and treatment target for presynaptic abnormalities in specific striatal regions in schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology, 35(5), 1226-1238. PMID: 20072114

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