The major aim of my research is to identify changes in the brains of individuals with schizophrenia, bipolar disorder and major depressive disorder that may elucidate the etiology of these disorders and provide clues to novel treatments. Current projects focus on white matter pathology and inflammation. In addition, we study the effects of antipsychotic medications on the brain.
Find most recent publications using my ORCID
Andreazza AC, Barakauskas VE, Fazeli S, Feresten A, Shao L, Wei V, Wu CH, Barr AM, Beasley CL. Effects of haloperidol and clozapine administration on oxidative stress in rat brain, liver and serum. Neurosci Lett. 2015 591:36-40. PMID: 25684243
Hercher C, Chopra V, Beasley CL. Evidence for morphological alterations in prefrontal white matter glia in schizophrenia and bipolar disorder. J Psychiatry Neurosci. 2014 39(6):376-385. PMID: 24936776
Feresten AH, Barakauskas V, Ypsilanti A, Barr AM, Beasley CL. Increased expression of glial fibrillary acidic protein in prefrontal cortex in psychotic illness. Schizophr Res. 2013 150(1):252-257. PMID: 23911257
Epp JR, Beasley CL, Galea LA. Increased hippocampal neurogenesis and p21 expression in depression: dependent on antidepressants, sex, age, and antipsychotic exposure. Neuropsychopharmacology. 2013 38(11):2297-2306. PMID: 23778854
Barr AM, Wu CH, Wong C, Hercher C, Töpfer E, Boyda HN, Procyshyn RM, Honer WG, Beasley CL. Effects of chronic exercise and treatment with the antipsychotic drug olanzapine on hippocampal volume in adult female rats. Neuroscience. 2013 255:147-157. PMID: 24141179
Vila-Rodriguez, F., Honer, W. G., Innis, S. M., Wellington, C. L., & Beasley, C. L. (2011). ApoE and cholesterol in schizophrenia and bipolar disorder: Comparison of grey and white matter and relation with APOE genotype. Journal of Psychiatry & Neuroscience : JPN, 36(1), 47-55. PMID: 20964956
Barakauskas, V. E., Ypsilanti, A. R., Barr, A. M., Innis, S. M., Honer, W. G., & Beasley, C. L. (2010). Effects of sub-chronic clozapine and haloperidol administration on brain lipid levels. Progress in Neuro-Psychopharmacology & Biological Psychiatry, 34(4), 669-673. PMID: 20227455
Barakauskas, V. E., Beasley, C. L., Barr, A. M., Ypsilanti, A. R., Li, H. Y., Thornton, A. E., Wong, H., Rosokija, G., Mann, J.J., Mancevski, B., Jakovski, Z., Davceva, N., Illevski, B., Dwork, A.J., Falkai, P., & Honer, W. G. (2010). A novel mechanism and treatment target for presynaptic abnormalities in specific striatal regions in schizophrenia. Neuropsychopharmacology : Official Publication of the American College of Neuropsychopharmacology, 35(5), 1226-1238. PMID: 20072114
